Highway 221

St. Francois County Highway 221 Opening Today

Missouri Department of Transportation officials say Route 221 in St. Francois County is set to reope...

Route 221 in St. Francois County is set to reopen to traffic Friday...

Construction on a section of Highway 221 west of Doe Run on Stono Hill, is going past its deadline.....

Roadside work to be performed on Route 221 next week...

The Thanksgiving holiday is one of the busiest travel periods of the year, ...

Multiple cases of Equine Herpes Myeloencephalopathy (EHM), the neurologic f...

The Missouri Governor’s Challenge to Prevent Suicide among Service Members,...

The Missouri Supreme Court is considering two major election-related lawsui...

Missouri Attorney General Catherine Hanaway has opened an investigation int...

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